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Index > Protein center > Cxadr(Gene name) > Mouse
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  • Cxadr (Gene name),
  • Coxsackievirus and adenovirus receptor homolog (Protein name ),  CXAR_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cxadr(Car);
    Protein name:
    Coxsackievirus and adenovirus receptor homolog(CAR;mCAR);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer. Probably homodimer formed by 2 molecules on adjacent cells. Interacts with LNX, MPDZ, BAIAP1, DLG4, PRKCABP, TJP1 and CTNNB1 (By similarity). Interacts with DNAJC7. Probably part of a complex containing CXADR, HSP90AA1 and DNAJC7.
    Function:
    In vitro, acts as a receptor for group B coxsackieviruses and subgroup C of adenoviruses (AD2 and AD5).
    Subcellular Location:
    Isoform 3 Secreted
    Protein Attributes:
    Sequence length:
    365
    Sequence:
    50:
    MARLLCFVLL | CGIADFTSGL | SITTPEQRIE | KAKGETAYLP | CKFTLSPEDQ | 
    100:
    GPLDIEWLIS | PSDNQIVDQV | IILYSGDKIY | DNYYPDLKGR | VHFTSNDVKS | 
    150:
    GDASINVTNL | QLSDIGTYQC | KVKKAPGVAN | KKFLLTVLVK | PSGTRCFVDG | 
    200:
    SEEIGNDFKL | KCEPKEGSLP | LQFEWQKLSD | SQTMPTPWLA | EMTSPVISVK | 
    250:
    NASSEYSGTY | SCTVQNRVGS | DQCMLRLDVV | PPSNRAGTIA | GAVIGTLLAL | 
    300:
    VLIGAILFCC | HRKRREEKYE | KEVHHDIRED | VPPPKSRTST | ARSYIGSNHS | 
    350:
    SLGSMSPSNM | EGYSKTQYNQ | VPSEDFERAP | QSPTLAPAKV | AAPNLSRMGA | 
    365:
    VPVMIPAQSK | DGSIV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    Pfam:
    UniGene:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse CAR
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    E13929r
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    Packing:
    96T
    ELISA Kit for Mouse CAR
    Cat.:
    E13929m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse CAR
    Cat.:
    E13929h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse CAR
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse CAR
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse CAR
    Cat.:
    U13929h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse CAR
    Cat.:
    U13929m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse CAR
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Mouse CAR
    Polyclonal Antibody for Mouse CAR
    Polyclonal Antibody for Mouse CAR
    Polyclonal Antibody for Mouse CAR
    Monoclonal Antibody for Mouse CAR
    Monoclonal Antibody for Mouse CAR
    Monoclonal Antibody for Mouse CAR
    Monoclonal Antibody for Mouse CAR
    Protein for Mouse CAR
    Protein for Mouse CAR
    Protein for Mouse CAR
    Protein for Mouse CAR

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses."
      Tomko R.P. , Xu R. , Philipson L.
      Proc. Natl. Acad. Sci. U.S.A.94:3352-3356(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY
      strain: C3H/Mai.
    2. 2.
      "Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5."
      Bergelson J.M. , Cunningham J.A. , Droguett G. , Kurt-Jones E. , Krithivas A. , Hong J.S. , Horwitz M.S. , Crowell R.L. , Finberg R.W.
      Science275:1320-1323(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION AS A VIRUS RECEPTOR
      strain: C57BL/6J.
      tissue: Colon.
      tissue: Liver.
    3. 3.
      "The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses."
      Bergelson J.M. , Krithivas A. , Celi L. , Droguett G. , Horwitz M.S. , Wickham T. , Crowell R.L. , Finberg R.W.
      J. Virol.72:415-419(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION AS A VIRUS RECEPTOR
      strain: C57BL/6J.
      tissue: Liver.
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Liver.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
      strain: FVB/N.
      tissue: Mammary gland.
    6. 6.
      "The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain."
      Honda T. , Saitoh H. , Masuko M. , Katagiri-Abe T. , Tominaga K. , Kozakai I. , Kobayashi K. , Kumanishi T. , Watanabe Y.G. , Odani S. , Kuwano R.
      Brain Res. Mol. Brain Res.77:19-28(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE;GLYCOSYLATION;FUNCTION
    7. 7.
      "Developmental distribution of coxsackie virus and adenovirus receptor localized in the nervous system."
      Hotta Y. , Honda T. , Naito M. , Kuwano R.
      Brain Res. Dev. Brain Res.143:1-13(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    8. 8.
      "Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs."
      Shaw C.A. , Holland P.C. , Sinnreich M. , Allen C. , Sollerbrant K. , Karpati G. , Nalbantoglu J.
      BMC Cell Biol.5:42-42(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-323;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    10. 10.
      "The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation."
      Witherden D.A. , Verdino P. , Rieder S.E. , Garijo O. , Mills R.E. , Teyton L. , Fischer W.H. , Wilson I.A. , Havran W.L.
      Science329:1205-1210(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN T CELL ACTIVATION;INTERACTION WITH CXADR
    11. 11.
      "The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells."
      Patzke C. , Max K.E. , Behlke J. , Schreiber J. , Schmidt H. , Dorner A.A. , Kroger S. , Henning M. , Otto A. , Heinemann U. , Rathjen F.G.
      J. Neurosci.30:2897-2910(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.19 ANGSTROMS) OF 20-233;DISULFIDE BONDS
    12. 12.
      "The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K."
      Verdino P. , Witherden D.A. , Havran W.L. , Wilson I.A.
      Science329:1210-1214(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 18-236 IN COMPLEX WITH AMICA1;DOMAIN;DISULFIDE BONDS;GLYCOSYLATION AT ASN-106
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